Endocrine Abstracts

Aims/hypothesis: Circulating erythropoietin (EPO) and vascular endothelial growth factor (VEGF) increase during hypoglycaemia and may represent a protective hormonal counter-regulatory response. We tested the hypothesis that low levels of EPO and VEGF are associated with a higher frequency of severe hypoglycaemia in a cohort of patients with type 1 diabetes.Methods: Two hundred and nineteen patients with type 1 diabetes (41% females, age 46±13 years...

Introduction: To investigate whether the incidence of severe hypoglycaemia in pregnant women with type 1 diabetes can be reduced without deteriorating pregnancy outcomes in a routine care setting.Methods/design: A new cohort (2009–2011) of 59 women receiving intensified education about the risk of severe hypoglycaemia in pregnancy was compared with an old cohort (2004–2006) of 108 women. The women entered the study at median 8 (range 5–13)...